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  • Title: [Microflora of the birth canal and an intrauterine catheter system following use of polyvinylpyrrolidone iodine for subpartal disinfection of the vaginal mucosa].
    Author: Kronjäger A, Weitzel H, Potel J, Schumann K.
    Journal: Z Geburtshilfe Perinatol; 1984; 188(1):29-33. PubMed ID: 6369816.
    Abstract:
    Changes in the microflora of the birth canal as a result of application of polyvinylpyrrolidone iodine were examined. 58 women in labor were randomly selected and assigned to a PVP iodine prophylaxis- and to a control group. Germinal spectra from cervical smears at the beginning of birth and directly post partum (p.p.) were taken, and bacteriological specimens from the intra-uterine catheter system and the oral cavity of the neonatus were also determined. In the p.p. cervical smears of the PVP iodine prophylaxis group, Escherichia coli (p = 0.05) were found significantly less frequently. The germinal isolates of the tip and middle of the catheter produced an increased occurrence of Pseudomonas aeruginosa and Klebsiella oxytoca. The frequency of these germs could be reduced significantly by vaginal application of PVP iodine. The oral cavity smear of the neonatus which was taken at the same time as the post partum cervical smear showed an almost identical bacterial flora. A reduction of E. coli and other gram-negative bacilli were found in the PVP iodine group.
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