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  • Title: [Therapeutic effect of Robaveron tablet (KN-7) on neurogenic bladder].
    Author: Endo H, Sonoda T, Koyanagi T, Maru A, Kuroda K, Takamura T, Inada F, Rokuzyo M, Ohori T, Kubo T.
    Journal: Hinyokika Kiyo; 1984 Jan; 30(1):135-44. PubMed ID: 6375318.
    Abstract:
    Therapeutic effect of Robaveron Tablet (KN-7) was studied on 128 patients suffering from neurogenic bladder. Robaveron Tablet was administered 6 tablets daily for 3 weeks. The effect was evaluated by the residual urine, subjective symptoms, cystometric findings, urethral pressure profile and uroflowmetry. Remarkable decrease of residual urine was observed regardless of position of injury. The pressure amplitude defined as the difference between the maximum voiding pressure and the maximum resting pressure increased on any group of neurogenic bladder. The effectiveness, rated as moderately improved or better was 76.9% for brain disorders, 58.3% for upper motor neuron lesion and 75.7% for lower motor neuron lesion of spinal injuries, 58.3% for peripheral nervous injuries and 100% for others. No remarkable abnormality was observed in the results of side effects or clinical laboratory tests.
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