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  • Title: Variations of biologic activity of low-dose prostaglandin E2 on cervical ripening.
    Author: Lorenz RP, Botti JJ, Chez RA, Bennett N.
    Journal: Obstet Gynecol; 1984 Jul; 64(1):123-7. PubMed ID: 6377145.
    Abstract:
    The effect of low-dose prostaglandin E2 vaginal gel specially prepared from commercially available materials, on subsequent indicated oxytocin induction of labor, was investigated in a randomized, double-blind, placebo-controlled clinical trial. The stability of the gel after preparation was documented by radioimmunoassay in vitro. No differences between the treated and placebo groups were noted in subsequent modified Bishop scores, length of labor, use of analgesia or anesthesia, success of induction, mode of delivery, or perinatal outcome. Comparisons of this clinical trial with those previously reported are offered.
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