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  • Title: Cyclosporin-associated central nervous system toxicity after allogeneic bone marrow transplantation.
    Author: Atkinson K, Biggs J, Darveniza P, Boland J, Concannon A, Dodds A.
    Journal: Transplantation; 1984 Jul; 38(1):34-7. PubMed ID: 6377609.
    Abstract:
    Five of 64 recipients of HLA-identical sibling marrow allografts who were given cyclosporin (CSP) to minimize graft-versus-host disease posttransplant had a serious neurological illness thought to be due to CSP. Characteristic clinical features included a motor spinal cord syndrome, a cerebellar-like syndrome, and mental confusion. All five recovered when the CSP dose was reduced or the drug was stopped.
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