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  • Title: Frequent isolation of Propionibacterium acnes from sarcoidosis lymph nodes.
    Author: Abe C, Iwai K, Mikami R, Hosoda Y.
    Journal: Zentralbl Bakteriol Mikrobiol Hyg A; 1984 Apr; 256(4):541-7. PubMed ID: 6377763.
    Abstract:
    Isolation of Propionibacterium acnes from biopsied lymph nodes of sarcoidosis patients and from the lymph nodes or other tissues of non-sarcoidosis patients was carried out, carefully avoiding contamination by skin-resident P. acnes. Out of 40 sarcoidosis lymph nodes examined, 31 nodes (77.5%) showed a positive culture of P. acnes, while 38 of 180 (21.1%) non-sarcoidosis tissues revealed positive results, the difference being significant (p less than 0.001). Among non-sarcoidosis tissues, the intra-thoracic lymph nodes demonstrated a positive culture in low percentages, while intra-abdominal lymph nodes indicated no positive culture. The possible role of this microorganism in the etiology of sarcoidosis is discussed.
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