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  • Title: Developmental biology of a neural cell adhesion molecule.
    Author: Rutishauser U.
    Journal: Nature; ; 310(5978):549-54. PubMed ID: 6379469.
    Abstract:
    A membrane glycoprotein isolated from embryonic brain has been shown to be a ligand in the formation of cell-cell bonds. The molecule, called neural cell adhesion molecule (N-CAM), participates in several aspects of neural development, including the formation of plexiform layers, neurite fasciculation and nerve-muscle interactions. Experiments in vivo indicate that N-CAM-mediated adhesion is essential to the orderly assembly of the visual system.
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