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  • Title: Transformation of arachidonic acid into thromboxane B2 by the homogenates of activated macrophages.
    Author: Murota SI, Kawamura M, Morita I.
    Journal: Biochim Biophys Acta; 1978 Mar 30; 528(3):507-11. PubMed ID: 638172.
    Abstract:
    The homogenates of activated macrophages obtained from liquid paraffin-injected guinea pig peritoneum were incubated with [14C]arachidonic acid or with radioactive prostaglandin endoperoside [14C]prostaglandin H2. The major radioactive metabolite in both cases was thromboxane B2, which was identified by NaBH4 reduction, rechromatography and autoradiography.
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