These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Effect of amphotericin B on phagocytosis and intracellular killing of E. coli by rat liver perfused in vitro: preliminary results].
    Author: Andreana A, Dilillo MA, Perna P, Ruggiero G.
    Journal: Boll Soc Ital Biol Sper; 1984 Jun 30; 60(6):1229-31. PubMed ID: 6383431.
    Abstract:
    Using isolated and perfused rat livers we found an inhibitory effect on intracellular killing of hepatic macrophages versus E. coli, in presence of therapeutic levels of amphotericin B (5 micrograms/ml). Since an interference of this antibiotic with phagocytic functions of human neutrophils has also been reported, we suggest that amphotericin B may exert a toxic effect on intraphagocytic microbicidal function, possibly by an interaction with membrane sterols.
    [Abstract] [Full Text] [Related] [New Search]