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  • Title: The effect of phalloidin on insulin secretion from islets of Langerhans isolated from rat pancreas.
    Author: Stutchfield J, Howell SL.
    Journal: FEBS Lett; 1984 Oct 01; 175(2):393-6. PubMed ID: 6383869.
    Abstract:
    Phalloidin, which stabilizes F-actin, has no effect on insulin secretion from intact islets, but penetrates and increases secretion from islets previously made permeable using a high voltage discharge technique. Use of this highly specific drug strongly suggests a role for microfilaments composed of F-actin in the insulin secretory process.
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