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  • Title: The gene and the pseudogene for mouse p53 cellular tumor antigen are located on different chromosomes.
    Author: Czosnek HH, Bienz B, Givol D, Zakut-Houri R, Pravtcheva DD, Ruddle FH, Oren M.
    Journal: Mol Cell Biol; 1984 Aug; 4(8):1638-40. PubMed ID: 6387444.
    Abstract:
    The chromosomal assignments of the two genes encoding the murine p53 cellular tumor antigen were determined by using a panel of mouse-Chinese hamster somatic cell hybrid clones and a mouse p53-specific cDNA clone. One gene, probably the functional member of the family, was found to be on chromosome 11. The other gene, which is probably a processed pseudogene, was assigned to chromosome 14. The potential relevance of these findings to documented cases of chromosome 11 trisomy are also discussed.
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