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  • Title: Recognition site of yeast glutathione reductase for 2'-phosphate of NADP+.
    Author: Tsai CS.
    Journal: Biochem Biophys Res Commun; 1984 Oct 30; 124(2):572-7. PubMed ID: 6388577.
    Abstract:
    Phenyl glyoxal in borate buffer specifically inactivates the NADPH-linked activity of yeast glutathione reductase. While NAD+ is ineffective, NADP+ prevents the enzyme from inactivation, and in the process, protects two arginine residues from glyoxalation. These two arginine residues presumably function as the recognition site for the anionic 2'-phosphate group of NADP+.
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