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  • Title: Response of monkeys to porcine zona pellucida as detected by a solid-phase radioimmunoassay.
    Author: Gulyas BJ, Yuan LC, Gwatkin RB, Schmell ED.
    Journal: J Med Primatol; 1983; 12(6):331-42. PubMed ID: 6389881.
    Abstract:
    The immunological response of cynomolgus monkeys (Macaca fascicularis) to immunization was evaluated utilizing collagenase-isolated pig zona pellucida. Six weeks after initial immunization a high serum titer of antibody was exhibited. Serum antibody titers demonstrated a noticeable decline 5 months after booster injections were discontinued. The assay method used is rapid and is capable of detecting antibody in serum dilutions of 1:78,000, as compared to 1:125,000 with the indirect fluorescence assay.
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