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  • Title: Scintigraphy in the diagnosis of osteonecrosis.
    Author: D'Ambrosia RD, Shoji H, Riggins RS, Stadalnik RC, DeNardo GL.
    Journal: Clin Orthop Relat Res; 1978; (130):139-43. PubMed ID: 639385.
    Abstract:
    Scintigraphy, using 99mTc diphosphonate, has the potential for diagnosing osteonecrosis before irreversible changes are visible in routine roentgenograms. If obtained within weeks of an avascular insult, a cold area will appear on scintiscan. However, months later, the revascularization and reparative processes of the dead bone produce a hot area on scintiscan.
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