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  • Title: [Hemo- and gas dynamic effects of artificial ventilation of the lungs].
    Author: Dvoretskiĭ DP, Tashliev VA, Nadyrshin RL, Vasil'ev AIu.
    Journal: Fiziol Zh SSSR Im I M Sechenova; 1984 Dec; 70(12):1666-72. PubMed ID: 6394366.
    Abstract:
    In anesthetized cats, autonomic respiration in the positive intermitting pressure mode induced a decrease of the minute blood volume under conditions of both the closed and the open chest by 24% and 43% resp. The arterial pressure in the major circulation as well as the pressure in the right heart ventricle were decreased insignificantly (by 10-15%). The mechanical respiration sharply increased the ratio: respiratory dead space volume/alveolar volume. To maintain the adequate values of the gaseous and acid-alkaline composition of arterial blood, it was necessary to set a considerably higher respiratory volume of the apparatus as compared with spontaneous breathing. Certain mechanisms of the artificial ventilation effects upon the cardiovascular and respiratory systems, are discussed.
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