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  • Title: [Collagenous sprue (author's transl)].
    Author: Riemann JF, Hofmann KP.
    Journal: Dtsch Med Wochenschr; 1978 Apr 21; 103(16):685-8. PubMed ID: 639716.
    Abstract:
    Malabsorption is the main functional abnormality in gluten-sensitive enteropathy or endemic sprue. The malabsorption is related to villous flattening, which is the main histological feature. The diagnosis is also based on a good response to gluten-free diet. On the other hand, collagenous sprue is not an independent disease but a variant of gluten-sensitive enteropathy, as documented in three personal cases. Its course is characterised by a malabsorption syndrome unresponsive to gluten withdrawal, with massive subepithelial collagen formation. The pathogenesis remains unknown, prognosis poor, compared to the endemic gluten-sensitive enteropathy.
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