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  • Title: Alkaline phosphatase isoenzymes in liver cirrhosis.
    Author: Burlina A, Bugiardini R.
    Journal: Enzyme; 1978; 23(2):121-6. PubMed ID: 639778.
    Abstract:
    The study of a group of 114 hepatic patients allowed us to demonstrate the presence of an isophosphatase band, called ALP4, which can be of value as an index of evolutive cirrhosis. A certain correlation between the presence of this alkaline phosphatase isoenzyme in serum and histological evidence of moderate or extreme inflammatory response in liver biopsies was shown.
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