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  • Title: [Vascular factors in the pathogenesis of pre-eclampsia: recent findings].
    Author: Foidart JM, Lambotte R.
    Journal: Rev Fr Gynecol Obstet; 1984 Apr; 79(4):249-52. PubMed ID: 6397832.
    Abstract:
    Normal, rigid and fibrotic utero-placental arteries are resistant to the action of circulating vaso-motor substances. In contrast, the persistence and the hyperplasia of smooth muscle fibres result in a reduced flow in the intervillous compartment and a sensitivity of the vessels to vaso-constrictor substances. These lesions, which develop after the twentieth week, provide the necessary conditions for the subsequent development of the characteristic vicious cycles of eclampsia.
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