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  • Title: Field evaluation of ELISA using Wuchereria bancrofti mf ES antigen for bancroftian filariasis.
    Author: Harinath BC, Malhotra A, Ghirnikar SN, Annadate SD, Isaacs VP, Bharti MS.
    Journal: Bull World Health Organ; 1984; 62(6):941-4. PubMed ID: 6398132.
    Abstract:
    An enzyme-linked immunosorbent assay using Wuchereria bancrofti microfilarial excretory-secretory antigen was used in field studies to screen blood samples collected on filter-paper from persons residing in areas endemic for bancroftian filariasis. This assay system, when compared with examination of night wet blood smears for microfilariae, gave a relative sensitivity of 98% and a relative specificity of 86%. Daytime blood samples can also be used in this test, which can thus replace tedious examination of night blood samples in field surveys in endemic areas.
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