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  • Title: Current experience with clindamycin in the treatment of abdominal and female pelvic infections.
    Author: Gorbach SL.
    Journal: Scand J Infect Dis Suppl; 1984; 43():82-8. PubMed ID: 6398909.
    Abstract:
    Clindamycin had been used in treatment of severe abdominal and female pelvic infections for over fifteen years. On the basis of several prospective trials, clindamycin has equivalent efficacy to other anti-anaerobe drugs such as cefoxitin and metronidazole. Clindamycin had proven to be superior to cephalothin, cefamandole and cefoperazone in intraabdominal infections. It also produces better results than various penicillins in a variety of obstetrical and gynecological infections. In one study, tubo-ovarian abscess healed significantly better on medical therapy when clindamycin was included in the regimen. Considering the long tract record of favorable results, clindamycin can be considered the "gold standard" by which other anti-anaerobe therapies of abdominal and female pelvic infections are judged.
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