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  • Title: Studies of autoimmunity in multiple sclerosis.
    Author: Whitaker JN, Snyder DS.
    Journal: CRC Crit Rev Clin Neurobiol; 1984; 1(1):45-82. PubMed ID: 6400508.
    Abstract:
    The central nervous system myelin unit (the myelin sheath and the supporting oligodendrocyte) may be damaged by a number of immune-mediated mechanisms involving cellular or humoral factors. In this review the following areas will be considered: the composition and properties of central nervous system myelin, the chemical and biological characteristics of oligodendrocytes, the participation of the central nervous system myelin unit in experimentally induced diseases, and a description and analysis of immunological abnormalities in humans with multiple sclerosis.
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