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  • Title: Klebsiella plasmid K21 is not involved in the aetiology of ankylosing spondylitis.
    Author: Ngo KY, Rochu D, D'Ambrosio AM, Muller JY, Lucotte G.
    Journal: Exp Clin Immunogenet; 1984; 1(3):140-4. PubMed ID: 6401143.
    Abstract:
    The possibility that a plasmid carried by Klebsiella pneumoniae plays a role in the pathogenesis of ankylosing spondylitis was explored. K. pneumoniae K21 contains a congruent to 25-kb plasmid, but this plasmid is not present in lymphocyte DNAs of ankylosing spondylitis HLA-B27 patients, as demonstrated by molecular hybridization experiments.
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