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  • Title: Respiration maintained by externally applied vibration and tracheal insufflation in the cat.
    Author: Bitterman H, Kerem DH, Shabtai Y, Gavriely N, Palti Y.
    Journal: Anesth Analg; 1983 Jan; 62(1):33-8. PubMed ID: 6401412.
    Abstract:
    It was reported recently that adequate gas exchange could be maintained in patients and experimental animals by applying very high-frequency (15 Hz), low-volume oscillations at the upper airways. This report deals with a new mode of high-frequency ventilation, in which gas exchange is achieved in paralyzed cats by externally vibrating the chest wall. These vibrations, which alone caused very small-volume (less than 0.5 ml) oscillations at the tracheal opening, maintained gas exchange at normal PaCO2 for hours when coupled with tracheal air insufflation. PaCO2 values as low as 15 torr could be achieved by increasing the insufflation rate. Vibration frequencies in the range of 20-45 Hz were equally effective. The method required little or no continuous positive airway pressure, caused little elevation of mean tracheal pressure, and no consistent changes in arterial and central venous pressures during ventilation. In addition to the potential merits of this method of ventilation, the described vibrations seem to considerably reduce the anatomic dead space and as such may assist conventional methods of artificial ventilation or even spontaneous breathing when rapid and shallow.
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