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  • Title: Prevalence of eosinophilia during gold therapy for rheumatoid arthritis.
    Author: Edelman J, Davis P, Owen ET.
    Journal: J Rheumatol; 1983 Feb; 10(1):121-3. PubMed ID: 6405032.
    Abstract:
    The prevalence of eosinophilia in 82 rheumatoid arthritis patients receiving gold sodium thiomalate (GSTM) and 30 patients receiving auranofin (AF) was determined in a retrospective study. Eosinophilia occurred in 21% taking GSTM and in 13% on AF. The simultaneous occurrence of toxicity and eosinophilia occurred in 14% receiving GSTM and in 10% receiving AF. In contrast, eosinophilia only occurred in 24% of those with suspected toxicity receiving GSTM and in 30% of those with suspected toxicity receiving AF. The value of eosinophilia as a marker of toxicity is discussed.
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