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  • Title: Comparative in vitro activity of Sch 29,482, a new oral penem, against Neisseria gonorrhoeae.
    Author: Khan MY, Gruninger RP, Nelson SM, Simpson ML.
    Journal: Antimicrob Agents Chemother; 1983 Mar; 23(3):481-2. PubMed ID: 6405687.
    Abstract:
    The in vitro activity of Sch 29,482, a new oral beta-lactam antimicrobial agent, was compared with those of norfloxacin, rosoxacin, ampicillin, erythromycin, and tetracycline against 142 Neisseria gonorrhoeae strains. Sch 29,482 was as active as norfloxacin and rosoxacin. Its activity was greater than the other three antimicrobial agents. It inhibited 90% of the isolates, regardless of beta-lactamase activity, at a concentration of less than or equal to 0.06 micrograms/ml.
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