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  • Title: Strain specific protective immunity against Trypanosoma cruzi.
    Author: Kloetzel JK, Lafaille JJ.
    Journal: J Parasitol; 1983 Apr; 69(2):267-70. PubMed ID: 6406657.
    Abstract:
    Swiss albino, C57BL/10J, and B10.A mice previously inoculated with an LD50 dose of T. cruzi Y strain were protected against subsequent challenge with the homologous strain, but had a parasitemia comparable to that of control mice when challenged with F strain trypomastigotes, although they were protected against mortality. In contrast, animals previously inoculated with an LD50 of T. cruzi F strain were protected both against a subsequent challenge with the homologous strain and the Y strain.
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