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  • Title: Extramedullary non-gastrointestinal plasmocytoma. An immunohistochemical study of sixteen cases.
    Author: Papadimitriou CS, Schwarze EW.
    Journal: Pathol Res Pract; 1983 Mar; 176(2-4):306-12. PubMed ID: 6406992.
    Abstract:
    Sixteen cases of extramedullary non-gastrointestinal plasmocytoma were studied for intracytoplasmic immunoglobulins by means of the immunoperoxidase-complex technique. Of the sixteen cases IgG class were observed in 4, IgM in one and IgA in 9 cases. Kappa light chains were found in 9 cases and lambda light chains in 6 cases. In one case a bitypic pattern of k- and lambda-positivity was encountered. In 2 cases only kappa light and no heavy chains were detected. The predominance of the IgA class in extramedullary, non-gastrointestinal plasmocytomas is in contrast to the prevalence of IgG type in multiple myeloma. The better possible behaviour of IgA-plasmocytomas is discussed further.
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