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Title: Failure of dorsal bundle lesions in rats to increase distractibility to a low intensity tone. Author: Dragunow M, Laverty R. Journal: Pharmacol Biochem Behav; 1983 May; 18(5):673-5. PubMed ID: 6407033. Abstract: Bilateral lesions of the dorsal noradrenergic bundle in rat brains with 6-hydroxydopamine produced a depletion of cortical noradrenaline to 19% of control values. Rats so treated showed resistance to extinction of a lever press task but no increased distractability from licking behaviour by a low intensity tone. These results cast doubt on the hypothesis that dorsal noradrenergic bundle lesions cause hyperdistractibility in rats.[Abstract] [Full Text] [Related] [New Search]