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  • Title: [Histomorphometry and karyometry studies of variably differentiated rectal cancers in humans before and after radiotherapy].
    Author: Wassilew G, Kranz D, Luschnikow EF, Zagrebin CM.
    Journal: Acta Histochem Suppl; 1983; 27():121-37. PubMed ID: 6408686.
    Abstract:
    Histo-morphometrical and karyometric examinations were carried out on biopsy and surgical samples from patients with cancer of the rectum. The aim of the examination was, to work out the structural morphometric characteristics of the differentiated cancer of the rectum high- and middle level and to list the quantitative morphological changes of the cancer caused irradiation with different total doses. The results of the histo-morphometric and karyometric examinations demonstrate, that both of the examined differential grades of the cancer differ less in their nucleus morphology but more in their composition of the parenchyma and stroma. Of the three total doses of irradiation the two doses using 2,500 and 4,000 rad proved to be effective as regards the structural changes of the tumor.
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