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  • Title: Iohexol in lumbar myelography: preliminary results from an open, noncomparative multicenter clinical study.
    Author: Eldevik OP, Nakstad P, Kendall BE, Hindmarsh T.
    Journal: AJNR Am J Neuroradiol; 1983; 4(3):299-301. PubMed ID: 6410725.
    Abstract:
    This is a preliminary report of the first clinical trials using iohexol as a contrast agent in lumbar myelography. The study was noncomparative and involved 82 adult patients in four centers. Iohexol doses of 10-15 ml (180 mg I/ml) were administered and clinical and laboratory tests were performed before and at intervals during 48 hr after myelography. Side effects were noted in 29 (35%) of 82 patients. Spinal repuncture 6 or 24 hr after myelography was performed in 51 patients. No significant increases in cerebrospinal fluid parameters were seen. No seizures or spikes on electroencephalography were seen.
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