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  • Title: Active and passive immunization against Pseudomonas aeruginosa infection of burned patients.
    Author: Roe EA, Jones RJ.
    Journal: Burns Incl Therm Inj; 1983 Jul; 9(6):433-9. PubMed ID: 6412970.
    Abstract:
    A 16-part polyvalent pseudomonas vaccine, PEV-01 and an immunoglobulin prepared from plasma from human volunteers vaccinated with PEV-01 were tested in a controlled clinical trial in burned patients at Safdarjang hospital, New Delhi. The mortality of the burned patients was reduced four-fold in adults and three-fold in children by the immunological treatments. Both immunoglobulin and vaccine increased the concentration of protective antibody. Patients responded to all 16 components in PEV-01. The vaccine caused no toxic side-effects and enhanced the bactericidal activity of polymorphonuclear leucocytes against Pseudomonas aeruginosa.
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