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  • Title: A cost-benefit analysis of a population screening programme for neural tube defects.
    Author: Sadovnick AD, Baird PA.
    Journal: Prenat Diagn; 1983; 3(2):117-26. PubMed ID: 6413966.
    Abstract:
    Population screening for neural tube defects is possible by measuring maternal serum alphafetoprotein levels with appropriate follow-up as required. British Columbia has approximately 39 000 births annually and the incidence of neural tube defects is 1.55 per 1000 births (0.94 per 1000 livebirths). Results from a cost-benefit analysis suggest that the outlined screening programme would be cost-beneficial for British Columbia. Other important factors essential to consider before instituting a population screening programme are discussed.
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