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  • Title: [Comparative analysis of the concentrations of lipid peroxidation products in the cerebral cortex, cerebrospinal fluid and peripheral blood during epileptic activity].
    Author: Kryzhanovskiĭ GN, Nikushkin EV, Voronko VA, Braslavskiĭ VE.
    Journal: Biull Eksp Biol Med; 1983 Nov; 96(11):36-8. PubMed ID: 6416329.
    Abstract:
    The development of focal or generalized epileptic activity (EA) in the rat brain cortex leads to the augmentation in the content of lipid peroxidation (LPO) products in the EA area (crude synaptosomes), diene conjugates, TBA-active products (products reacting with 2-thiobarbituric acid), and Schiff bases. LPO activation in the brain cortex during EA leads both to an increase in the level of Schiff bases in the cerebrospinal fluid and to a dramatic rise in the level of diene conjugates and Schiff bases in peripheral blood plasma.
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