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  • Title: [Heterotopic ossification in the skeletal muscle metastases of advanced stomach cancer].
    Author: Fujiwara R, Saga T, Akashi N, Takegoshi T, Saitoh K, Tokuda T, Kitoh C, Ichiyanagi K, Doishita K.
    Journal: Gan No Rinsho; 1983 Oct; 29(12):1471-5. PubMed ID: 6417371.
    Abstract:
    The formation of heterotopic bone tissue in carcinomas of the gastrointestinal tract and/or their metastases is extremely rare. In a 74-year-old female with gastric adenocarcinoma, we observed extensive bone formation within metastases in the skeletal muscles. There are only 7 other cases of heterotopic bone formation in gastric cancer reported in the world literature. We suggest that heterotopic ossification in primary cancers and/or their metastases is probably the result of metaplasia of stromal fibroblasts into osteoblasts.
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