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  • Title: [Precocious puberty in boys. Study of a series of 34 cases].
    Author: Blanco-Garcia M, Job JC, Chaussain JL, Canlorbe P.
    Journal: Arch Fr Pediatr; 1983 Oct; 40(8):637-42. PubMed ID: 6418108.
    Abstract:
    Thirty-four boys with true precocious puberty were observed: In 28, precocious puberty was related to intracranial causes (17 tumors, 11 other lesions), in 3, it was due to extrapituitary gonadotropin-secreting tumors and in 3 it appeared idiopathic. The clinical development of sex characteristics was slower than the advance of bone age and the increase in hormone levels (plasma testosterone and pituitary gonadotropin reserve as measured by the LH-RH test). Cyproterone treatment seemed more effective than medroxyprogesterone, with respect to both sexual development and evolution of the bone age/height age ratio or the predictable adult height.
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