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  • Title: Factor VIII-related antigen in Kaposi's sarcoma in young homosexual men.
    Author: Flotte TJ, Hatcher VA, Friedman-Kien AE.
    Journal: Arch Dermatol; 1984 Feb; 120(2):180-2. PubMed ID: 6421251.
    Abstract:
    This study investigated the histogenesis of the Kaposi's sarcomas occurring in young homosexual men. Paraffin sections of seven tumors were stained for factor VIII-related antigen by the unlabeled peroxidase antiperoxidase method. Both the spindle cell component and the cells lining vascular channels contained factor VIII-related antigen, a marker for endothelial cells. Our study supports the hypothesis that both components of Kaposi's sarcoma are of endothelial cell origin.
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