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  • Title: Phase II trial of ICRF-187 in squamous cell carcinoma of the head and neck.
    Author: Wheeler RH, Bricker LJ, Natale RB, Baker SR.
    Journal: Cancer Treat Rep; 1984 Feb; 68(2):427-8. PubMed ID: 6421483.
    Abstract:
    A phase II trial of ICRF-187 (1.0 g/m2/48 hours by continuous infusion every 3 weeks) was conducted in 25 patients with advanced squamous cell cancer of the head and neck. There were two partial responders for an overall response rate of 8%. Sixteen of the patients had not received prior chemotherapy and both responding patients were in this group. The major side effect of ICRF-187 was reversible leukopenia.
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