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  • Title: [Effect of a glucose load on lipid metabolic indices in coronary arteriosclerosis with varying types of hyperlipoproteinemia].
    Author: Bobkova VI, Sidakova NM, Fomchenkov SI.
    Journal: Kardiologiia; 1978 Mar; 18(3):66-73. PubMed ID: 642243.
    Abstract:
    The dynamics of changes in the indices of lipid metabolism was studied in 130 patients with coronary atherosclerosis and different types of hyperlipoproteinemia (HLP) during 3 hours of the standard glucose tolerance test. It was established that a single glucose load in patients with coronary atherosclerosis caused insufficient decrease in the level of NEFA in the blood, and sometimes even led to its paradoxical increase, and parallel accumulation of cholesterol and triglycerides in the blood to a different degree in different patients. Significant differences were revealed in the changes in the lipid composition of blood in response to glucose load in patients with type IIa and type IV HLP. Analysis of the hypolipidemic effect of miscleron and liniksin depending on the type of HLP and on the reaction of the lipid metabolism indices to the conditions of a glucose load showed that besides determining the type of HLP in patients with coronary atherosclerosis it is expedient to study the dynamics of changes in the blood lipid composition after glucose intake.
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