These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effect of a diphosphonate on the osteoinductive activity of rat bone matrix.
    Author: Bauer FC, Nilsson OS, Tornkvist H, Lindholm TC, Lindholm TS.
    Journal: Clin Orthop Relat Res; 1984 May; (185):266-9. PubMed ID: 6423335.
    Abstract:
    Implants of demineralized allogeneic bone were investigated to determine the effects of ethane-1-hydroxy-1,1-diphosphonate (EHDP) on the osteoinductive effect of bone matrix. Implants of matrix prepared from bones of rats treated by EHDP (20 mg/kg/day) produced 40% less ash than implants of normal bone matrix. These results indicate that EHDP not only interferes with mineralization but also has a direct effect on protein metabolism of bone cells.
    [Abstract] [Full Text] [Related] [New Search]