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  • Title: [R-(Z)]-4-amino-3-chloro-2-pentenedioic acid, a new antibiotic. Fermentation, isolation and characterization.
    Author: Chaiet L, Arison BH, Monaghan RL, Springer JP, Smith JL, Zimmerman SB.
    Journal: J Antibiot (Tokyo); 1984 Mar; 37(3):207-10. PubMed ID: 6427163.
    Abstract:
    A new unsaturated glutamic acid analog, 4-amino-3-chloro-2-pentenedioic acid ( ACPA ) was isolated from a fermentation broth produced by a strain of Streptomyces. ACPA has a very narrow antibacterial spectrum, which is virtually limited to Micrococcus luteus.
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