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  • Title: Concentration of In-111-oxine-labeled autologous leukocytes in noninfected and nonrejecting renal allografts: concise communication.
    Author: Collier BD, Isitman AT, Kaufman HM, Rao SA, Knobel J, Hellman RS, Zielonka JS, Pelc L.
    Journal: J Nucl Med; 1984 Feb; 25(2):156-9. PubMed ID: 6427429.
    Abstract:
    Autologous leukocytes labeled with In-111 oxine (ILL) concentrated in the renal allografts of eight patients for whom transplant rejection, infection, or acute tubular necrosis (ATN) could be excluded. All patients had good-to-adequate renal function at the time of ILL scintigraphy, and none developed rejection or renal transplant failure during a 1-mo follow-up period. It is concluded that normally functioning renal allografts without evidence of rejection, infection, or ATN often will concentrate ILL. When a baseline study is not available for comparison, this phenomenon limits the value of ILL scintigraphy as a diagnostic test for transplant rejection or infection.
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