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  • Title: Simplified gentamicin dosing in neonates: a time- and cost-efficient approach.
    Author: Leff RD, Andersen RD, Roberts RJ.
    Journal: Pediatr Infect Dis; 1984; 3(3):208-12. PubMed ID: 6429646.
    Abstract:
    A nomogram-based method for monitoring gentamicin therapy in neonates was developed and evaluated prospectively. Gentamicin dosage adjustment, based on analysis of a single blood sample collected between 8 and 12 hours after dose administration, resulted in satisfactory serum levels in 79% of the neonates. When compared to dosage adjustment methods requiring multiple blood samples, the nomogram method is a cost-effective and time-efficient technique for screening the appropriateness of gentamicin dosages in neonates.
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