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  • Title: Amphetamine anorexia: the effect of radio-frequency lesions and 6-OHDA injections into dopaminergic nigro-striatal bundle in cats.
    Author: Konopacki J.
    Journal: Pol J Pharmacol Pharm; 1983; 35(6):497-502. PubMed ID: 6429650.
    Abstract:
    The effect of radio-frequency (RF) and 6-OHDA lesions of two levels of dopaminergic nigro-striatal bundle on amphetamine anorexia was investigated in 4 groups of cats. RF and 6-OHDA lesions of far-lateral hypothalamus produced significant facilitation of feeding after injection of amphetamine. RF and 6-OHDA destructions of substantia nigra were with slight or without (respectively) effect on amphetamine anorexia. The results suggest that nigrostriatal bundle is not essential for mechanisms mediating amphetamine anorexia.
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