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  • Title: Lithium-induced accentuation of extrapyramidal symptoms in individuals with Alzheimer's disease.
    Author: Kelwala S, Pomara N, Stanley M, Sitaram N, Gershon S.
    Journal: J Clin Psychiatry; 1984 Aug; 45(8):342-4. PubMed ID: 6430878.
    Abstract:
    Lithium treatment in 9 elderly individuals with Alzheimer's disease led to a marked accentuation of extra-pyramidal symptoms (EPS) in 5 of 6 patients with preexisting EPS. EPS scores significantly correlated with plasma and RBC lithium levels. Lithium treatment had no such effects in the 3 patients without preexisting extrapyramidal symptoms.
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