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  • Title: [Imaging of blood flow-dependent curve parameters in the course of sequential computed tomography of the kidneys following intravenous injection of a contrast bolus].
    Author: Jaschke W, Lipton M, Cann C, Sievers R.
    Journal: Rofo; 1984 Jul; 141(1):1-7. PubMed ID: 6431504.
    Abstract:
    Since the introduction of fast CT scanners with short scanning times the early density changes observed during the first transit of a contrast bolus can be clearly demonstrated and quantified. A theoretical curve can be fit to the CT data describing the density changes in the kidney according to the indicator dilution principle. A curve parameter can be obtained which characterizes the shape of the curve. Then an image can be calculated which reflects the selected curve parameter rather than tissue densities. Such images have been termed "functional images". Using this type of imaging we were able to demonstrate acute changes in renal perfusion.
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