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  • Title: Absence of H-Y antigen in a case of sporadic pure gonadal dysgenesis.
    Author: Boucekkine C, Benmiloud M, Himeur B, Chouiter A, Bachammar M.
    Journal: J Endocrinol Invest; 1984 Jun; 7(3):225-30. PubMed ID: 6432892.
    Abstract:
    H-Y activity, endocrine function and gonadal histology were studied in a phenotypic female presenting with features of sporadic 46,XY pure gonadal dysgenesis. H-Y activity was absent, hormonal data revealed a primary ovarian failure with a blunted response of FSH to LHRH; there was no testicular tissue nor microscopic evidence of gonadal tumor in the gonads. The current view on the role of H-Y antigen in the differentiation of the gonads and in the occurrence of gonocytoma is discussed.
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