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  • Title: [Impaired function of the sympatho-adrenal system in patients with esophageal and stomach cancer].
    Author: Tarutinov VI, Paliukh VB, Vinnitskiĭ VB, Shmal'ko IuP, Balitskiĭ KP.
    Journal: Vopr Onkol; 1984; 30(8):60-7. PubMed ID: 6435311.
    Abstract:
    Patients with esophageal and gastric cancer show a decreased diurnal excretion of DOPA matched by a considerable drop in the urine levels of catecholamines and their main metabolites as compared with healthy subjects. This points to a severe inhibition of synthesis and metabolism of catecholamines at all stages. Tumor process progression is accompanied by an ever-increasing inhibition of sympatho-adrenal system function. Simultaneously, disorders develop in the functioning of the cholinergic structures of the nervous system.
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