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  • Title: Action of suriclone in naturally and allyglycine-induced photosensitive baboons, Papio papio.
    Author: Stutzmann JM, Cepeda C, Naquet R.
    Journal: Exp Neurol; 1984 Nov; 86(2):379-87. PubMed ID: 6436048.
    Abstract:
    Suriclone (SC) is a new anxiolytic compound with a chemical structure different from that of benzodiazepines (BZD) but SC possesses a high affinity for the so-called BZD receptors. SC was tested in the naturally or the allylglycine-treated photosensitive baboon Papio papio. As active BZD administered by the intramuscular or oral route, this new compound possesses a marked protective effect against the excessive photosensitivity of the baboons, it blocks myoclonus following EEG spike and waves discharges induced by intermittent light stimulation; as BZD again, SC can induce spontaneous myoclonus not accompanied by EEG spike and wave discharges.
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