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  • Title: [Adjuvant chemotherapy after surgery in advanced gastric cancer].
    Author: Hirose S, Mano K, Kataoka K, Kitamura M, Tsutsui N, Ohara T, Kimura H, Hamaya K.
    Journal: Gan No Rinsho; 1984 Nov; 30(14):1767-72. PubMed ID: 6439912.
    Abstract:
    Two hundred and fifty-four patients with advanced gastric cancer underwent radical surgery and ftorafur (FT) or 5-fluorouracil (5-FU) was orally administered as the adjuvant chemotherapy (ACT). Recurrence after ACT were analyzed by the quantification method II. As a result, it was found that: 1) ACT over 2 years could lower the recurrence rate, and careful follow-up is still necessary up to 4 years, and 2) after the remission induction therapy with mitomycin C and/or 5-FU and cytarabine, 12 mg/kg/day of FT for the first year and 8 mg for the second year are advisable.
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