These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The effect of nerve growth factor and its antibodies on neurofilament protein expression in primary cultures of sensory and spinal neurons.
    Author: Doherty P, Dickson JG, Flanigan TP, Walsh FS.
    Journal: Neurosci Lett; 1984 Sep 28; 51(1):55-60. PubMed ID: 6440067.
    Abstract:
    An enzyme-linked immunoadsorbent assay has been used to quantify the binding of an antineurofilament monoclonal antibody, RT97, to primary cultures of embryonic chick dorsal root ganglion and spinal cord tissue. In the case of dorsal root ganglion cells a dose-dependent relationship between nerve growth factor (NGF) concentration and the level of RT97 binding was observed. This response could be antagonised by an anti-serum directed against NGF. In contrast, neither NGF nor the antiserum against NGF influenced the binding of RT97 in primary cultures initiated from chick spinal cord.
    [Abstract] [Full Text] [Related] [New Search]