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  • Title: Influence of trapidil derivatives on arachidonic acid- and prostaglandin endoperoxide analogue- induced platelet aggregation and thromboxane A2 formation.
    Author: Heinroth I, Block HU, Mest HJ.
    Journal: Biomed Biochim Acta; 1984; 43(8-9):S389-92. PubMed ID: 6440555.
    Abstract:
    Five selected trapidil derivatives (12456, 12460, 12463, 12464, 12465) inhibited the arachidonic acid(AA)- and prostaglandin endoperoxide analogue(U-46619)- induced platelet aggregation as well as the AA- induced thromboxane A2(TXA2) formation. These effects of the derivatives were generally more markedly expressed than those of trapidil.
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